ĐÁNH GIÁ ĐỘC TÍNH CẤP VÀ BÁN TRƯỜNG DIỄN CỦA CHẾ PHẨM CHỐNG HÔI CHÂN
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Tóm tắt
EVALUATION OF THE ACUTE AND SUBCHRONIC TOXICITY OF FOOT ANTI-ODOR PRODUCT
In this study, the acute and subchronic toxicity of foot anti-odor product made from laurate salt is evaluated. The results show that the median lethal dose, LD50 of the product hasn’t been found in mice tested with maximum oral dosage . At the dosage of 200 and 400 mg/kg/24h on rabbit, the continuously oral administration for 42 days doesn’t affect the normal weight increment of rabbit and doesn’t change the electrocardiogram; hematological indices such as red blood cell, white blood cell, platelet and hemoglobin content, hepatic indices (AST, ALT activity), renal indices (urea, creatinine levels) are found within normal limits
Từ khóa
Foot antiodor product, LD50, subchronic, acute toxicity, chống hôi chân, độc tính cấp, bán trường diễn
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Tài liệu tham khảo
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