NGHIÊN CỨU ĐỘ NHẠY CẢM KHÁNG SINH CỦA CÁC CHỦNG STREPTOCOCUS NHÓM A, C, G PHÂN LẬP TỪ NHẦY HỌNG HỌC SINH TIỂU HỌC GIAI ĐOẠN 2012 - 2015
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Tóm tắt (Abstract)
ASSESSMENT OF ANTIBIOTIC SUSCEPTIBILITY IN STREPTOCOCCI GROUPS A, C, G ISOLATED FROM THROAT MUCUS OF PRIMARY SCHOOL PUPILS IN THE PERIOD 2012 - 2015
Antibiotic resistance is a global problem, and serious threat to human health. Study on antibiotic susceptibility in streptococci strains group A, C, G isolated from primary school pupils in Viet Nam during 2012÷2015 showed that all streptococci strains were susceptible to cefalosporins and vancomycin as well, simultaneous resistance to amikacin. The resistant rate of GAS to tetracycline and doxycillin were 70% and 75%, respectively. The rate of erythromycin tolerance of GAS was 52.5% and 40.74% in that of GCS/GGS. The third and fourth generation cephalosporin antibiotic group and vancomycin are considered as essential drugs for treating group A, C and G streptococcal infections. The correlation between mefA and ermTR genes in streptococci genome in the macrolide resistant mechanism were not detected. A tetracycline resistant gene in the jumping gene of the GAS genome was found.
Từ khóa (Keywords)
Kháng kháng sinh, liên cầu khuẩn, Antibiotic resistance, streptococci
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Tài liệu tham khảo
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